Release Notes ============= Version 0.4.2 (2019-12-26) """""""""""""""""""""""""" - Fixed bugs related to HMM training failures - Added *domaincaller* and *visualize* modules Version 0.4.1 (2019-05-03) """""""""""""""""""""""""" - Improved command-line options Version 0.4.0 (2018-11-24) """""""""""""""""""""""""" - Migrated to Python 3 (will not support Python 2 anymore) - *Cool* support - Added two handy scripts *tad-plot* and *output-DI* - Changed to *pomegranate* for HMM learning Version 0.3.1-r1 (2017-8-18) """""""""""""""""""""""""""" - Fixed a bug in the definition of conserved TADs Version 0.3.1 (2017-7-19) """""""""""""""""""""""""""""" - Improved the performance of HiTAD by modifying the objective function used in the TAD and sub-TAD detection procedure. - Streamlined the log and the code documentation. - Added a new method named *convertMatrix* to *tadlib.calfea.analyze.Core*. - Migrated the documentation site from PyPI to Github Version 0.3.0-dev2 (2017-5-28) """""""""""""""""""""""""""""" - Removed the ``--cache`` option from *hitad* command-line tool. Version 0.3.0-dev1 (2017-5-2) """"""""""""""""""""""""""""" - Added the HiTAD module for hierarchical TAD detecting Version 0.2.5-r2 (2016-4-14) """""""""""""""""""""""""""" - TADLib will not support python2.6 anymore Version 0.2.5-r1 (2015-11-10) """"""""""""""""""""""""""""" - Only check for update when you are online Version 0.2.5 (2015-11-7) """"""""""""""""""""""""" - Added snippets for automatic update checking - Added a log handler for the import case Version 0.2.4 (2015-4-14) """"""""""""""""""""""""" - Changed the significant interaction selection algorithm - Removed the TAD identification module based on the controversial constrained hierarchical clustering algorithm Version 0.1.0 (2014-11-25) """""""""""""""""""""""""" - The first release containing the Aggregration Preference(AP) calculation module and an optional TAD identification module