Release Notes ============= Version 0.8.7 (01/19/2023) -------------------------- - Made the program compatible with pairtools v1.0.2 Version 0.8.6 (05/24/2022) -------------------------- - Added support for other 3C-based experiments that do no use restriction enzymes for DNA fragmentation Version 0.8.5 (08/15/2021) --------------------------- - changed the default read aligner to chromap - made the fragment-level filtering optional - removed the "-O/--outformat" argument Version 0.8.4-r1 (01/16/2021) ------------------------------ - Added the "--high-res" option to ``runHiC pileup`` and ``runHiC binning``. Version 0.8.4 (01/03/2021) -------------------------- - Changed the bwa parameters from "bwa mem -SP" to "bwa mem -SP5M" - Changed the default walks policy from "mask" to "all" - Fixed a bug pertaining to the FASTQ read format. In previous versions, error will occur when there is "." in the prefix of FASTQ file names. - Added a piechart function to ``runHiC quality``. - Added a function to automatically output mcool in the final step. - Added a function to automatically check and remove invalid link files within the "filtered" sub-folder - Fixed a bug to avoid duplicate operations when only one replicate exists - Added a function to automatically sort chromosome names. Numerical labels will be sorted natually; for non-numerical labels, give priority to XYM over the rest. Version 0.8.3 (03/04/2019) -------------------------- - Parallelized statistics collecting - Reduced the computational overhead in the filtering step Version 0.8.2 (01/16/2019) -------------------------- - Fixed a bug pertaining to large dataset overflow in binning (by increasing the value for ``--max-split``) Version 0.8.1 (12/23/2018) -------------------------- - Added support for Arima Hi-C Version 0.8.0 (09/16/2018) -------------------------- - Migrated to Python 3 (will not support Python 2 anymore) - Changed the data container from HDF5 to Pairs and Cooler - Added two aligner options: bwa-mem (short reads) / minimap2 (long reads) - Added options to output filtered SAM/BAM for further analysis Version 0.7.0 (10/29/2017) --------------------------- - Parallelized the execution on both laptops and PBS-based clusters. - Included the latest *mirnylib* and *hiclib* source code. - Tuned the class/function interfaces in sync with the lastest *hiclib*. - Removed the *visualize* subcommand. - Changed the default "--chroms" setting to "['#','X']" - Refined the logging information. - Added the detailed documentations. Version 0.6.6-r2 (05/04/2016) ----------------------------- - Fixed a bug related to "--bowtieIndex". - Included LICENSE. Version 0.6.6-r1 (11/10/2015) ----------------------------- - Only check for update when you are online. Version 0.6.6 (11/06/2015) -------------------------- - Removed redundant command-line arguments. - Added detailed descriptions for the quality assessment module in Recipes.rst. - Added snippets for automatic update checking. Version 0.6.5 (09/29/2015) -------------------------- - More sophisticated quality assessment module. - Changed the filtering settings for *pileup*. - Redirected the exception information into the log file. Version 0.6.4 (09/21/2015) -------------------------- - Fixed a bug related to the metadata loading. Version 0.6.3 (09/16/2015) -------------------------- - Customized the mirnylib Genome class by overriding the *_extractChrmLabel* method. Version 0.6.2 (08/21/2015) -------------------------- - Added the *visualize* subcommand. Version 0.6.1 (07/21/2015) -------------------------- - Improved the logging system. Version 0.6.0 (06/16/2015) -------------------------- - Fixed a bug for bam file parsing in the case of FASTQ read format.